PRIMA
PRIMA Celiac Test
PRIMA Celiac Test
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CELIAC DISEASE & ANTI-DGP ANTIBODIES
Celiac disease is a chronic autoimmune disorder that involves the inflammation of the small intestine due to gliadin intake: the protein portion of gluten found in various cereals (oats, wheat, barley, kamut, spelled, rye, spelled and triticale).
Gliadin is a water-soluble peptide that acts as “glue”, helping to maintain the shape of food, and able to pass through the intestinal epithelium. Recent studies have shown that people who suffer from celiac disease produce specific antibodies against gliadin deamidated peptides (anti-DGP), IgA and IgG, as a result of transglutaminase, which shows high specificity and sensitivity for celiac disease, thus allowing high accuracy in disease screening.
WHO IS THIS TEST FOR?
CELIAC TEST is useful for anyone who wants to check for any gluten sensitivity, which must then be confirmed by a specialist.
In particular, it is addressed to all those who have symptoms related to celiac disease, such as abdominal pain and swelling, chronic diarrhea, constipation, vomiting, weight loss and irritability, or for those who are genetically familiar with the disease. Even in the absence of the symptoms listed above, it is useful in case of iron, vitamin B or folate deficiency, which could indicate an incorrect intake of essential nutrients.
TECH SPECS
CELIAC TEST is a lateral flow immunochromatographic device for the detection of IgA and IgG anti-DGP antibodies in whole blood. If antibodies are present in the sample, they will react with the deamidated gliadin. A positive result indicates that the antibody concentration is close to the cut-off of 20 U/mL.
| Specificity | 94.1% |
| Sensitivity | 81.25% |
| Accuracy | 90.0% |
*** Disclaimer: This test does not replace receiving medical advise. If you have any concerns for your health, please visit your healthcare professional ***
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